- 15-11-2022In 2017, the European Commission installed 24 European Reference Networks (ERN) for different categories of rare and complex conditions to…
- 15-11-2022BackgroundPrevious research has shown that bone mineral density (BMD) Z-scores decrease during puberty suppression in transgender adolescents, with incomplete catch-up…
- 15-11-2022Background: Treatment in trans girls can consist of puberty suppression with GnRHa followed by estrogen treatment. A decrease in bone…
- 15-11-2022IntroductionDopamine agonists (DA) are first-line treatment for prolactinomas and effectively control hyperprolactinemia in most patients. However, side effects may negatively…
- 15-11-2022BackgroundSurvival in childhood craniopharyngioma (CP) is excellent, however survivors face many sequelae of the tumor and its treatment, mainly caused…
- 14-11-2022In recent years, there has been wide interest in the use of dried blood spots (DBS) for research and diagnostic…
- 14-11-2022Cushing’s disease is a rare and often difficult diagnosis. Therefore, a significant delay between the onset of symptoms and the…
- 14-11-2022Background A low concentration of Sex Hormone Binding Globulin (SHBG) is associated with type 2 diabetes, metabolic syndrome, and fatty…
- 14-11-2022BackgroundLow levels of sex hormone binding globulin (SHBG) and fatty liver are related to an increased risk of type 2…
- 14-11-2022Objective: International guidelines recommend to diagnose gestational thyroid disease according to trimester-specific reference intervals (RIs) for TSH and FT4. Yet,…