- 14-11-2022Background:Growth hormone deficiency (GHD) in children is one of many causes for short stature. GHD in childhood may or may…
- 14-11-2022BackgroundPasireotide is a second-generation somatostatin receptor ligand (SRL) with proven efficacy for the treatment of acromegaly, although treatment-emergent hyperglycemia can…
- 14-11-2022In women, elevated levels of androgens, such as in PCOS, increase the risk of obesity and diabetes. Altered adipose tissue…
- 14-11-2022Background: Lenvatinib is a multitarget tyrosine kinase inhibitor (TKI) approved for the treatment of metastatic differentiated thyroid cancer (TC). The…
- 14-11-2022Ghrelin is a gut hormone that enhances food intake and growth hormone secretion through its receptor, the G-protein coupled receptor…
- 14-11-2022Achtergrond: De registratie van medicatie voor zeldzame aandoeningen wordt bemoeilijkt door beperkte mogelijkheden voor placebogecontroleerde studies. In 2020 startte het…
- 14-11-2022Background Autoimmune diseases are more common in women than in men. Generally, estrogen has an immunoenhancing effect, while testosterone has…
- 14-11-2022IntroductionHypothalamic dysfunction (HD) during childhood can occur due to (treatment of) a suprasellar brain tumor. HD may not only result…
- 14-11-2022IntroductionGraves’ Disease (GD) is an auto-immune disease characterized by an upregulated thyroid hormone (TH) production. GD is diagnosed by measuring…
- 14-11-2022IntroductionCongenital hypothyroidism (CH), an inborn thyroid hormone (TH) deficiency, is mostly caused by disturbances at the level of the thyroid…
