- 07-11-2018Growth hormone (GH) secretion is pulsatile and highly variable between individuals. However, we commonly reduce the outcomes of the complex…
- 07-11-2018IntroductionIndividuals with Prader-Willi syndrome (PWS) have deficiencies of several hypothalamic-pituitary axes. Studies have reported differing prevalences of central adrenal insufficiency…
- 06-11-2018BACKGROUND Insulinomas are rare neuroendocrine tumors originating from pancreatic beta-cells. The estimated incidence of insulinomas is 1:250.000 persons/year. We present…
- 06-11-2018A 40-year-old Indian female patient presented with hirsutism. She had excess hair growth, especially on her face since 2015. Examination…
- 06-11-2018Introduction:Multiple endocrine neoplasia type 2A (MEN2A) syndrome caused by a pathogenic germline mutation in the RET protooncogene, is amongst other things…
- 06-11-2018Background: Variation in karyotype may be associated with the phenotype of patients with Turner syndrome (TS). Our objective was to…
- 06-11-2018Derailment of the endocannabinoid system by high fat diet starts in adipose tissueEline N. Kuipers1#, Vasudev Kantae2#, Boukje C. Eveleens…
- 06-11-2018Background and aimsA recent randomized controlled, 26-week clinical trial has shown that continuous subcutaneous insulin infusion (CSII) using a simple…
- 06-11-2018OBJECTIVE: The increased use of opioids has resulted in an unprecedented opioid epidemic. It is known that chronic opioid use…
- 06-11-2018Glucocorticoids can strengthen or impair memory consolidation via glucocorticoid receptor (GR) transcriptional mechanisms. GR-mediated transcription is highly context-dependent and relies…
