- 06-09-2018Craniopharyngiomas (CP) are benign tumors in the sellar region with an aggressive local behavior. CP patients with have an adverse…
- 06-09-2018Background Glucocorticoids regulate pivotal processes such as metabolism and inflammation via the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR).…
- 05-09-2018Glucocorticoids potently enhance memory consolidation after emotional events, in a strictly noradrenaline-dependent way. This suggests an interaction of two transcription…
- 04-09-2018Aim: The past decade, it has become evident that circadian (i.e. 24 h) rhythms within metabolically active tissues are very…
- 03-09-2018BackgroundThe Dutch neonatal screening program effectively detects both primary and secondary congenital hypothyroidism (CH). This unique feature provides the ability…
- 01-09-2018ObjectivePTH can be oxidised in vivo, rendering it biologically inactive. Non-oxidised PTH (n-oxPTH) may therefore give a better image of…
- 31-08-2018BackgroundDexamethasone (DEX) is a commonly used drug, but can cause severe neuropsychiatric effects, like depression, delirium and mania. As DEX…
- 31-08-2018Introduction: Blood metabolic profiling is a promising approach for gaining novel insights into early metabolic changes preceding the onset of…
- 30-08-2018BackgroundFirst line treatment for prolactinoma patients is with a dopamine agonist (DA). Endoscopic trans-sphenoidal resection is reserved for patients with…
- 20-08-2018Background: Glucocorticoids exert a myriad of metabolic effects mediated predominantly via binding to the glucocorticoid receptor (GR). The GR is known…
