- 11-10-2018Primary human bone marrow stromal cells (BMSCs) have been considered as an ideal source for the use in regenerative medicine.…
- 11-10-2018Introduction: Musculoskeletal (MSK) injuries are common. Several genetic loci have been implicated. This study aimed to develop a “machine learning”…
- 11-10-2018Background: MEIS1 is an important transcriptional regulator in hematopoietic development. Previous studies illustrated MEIS1 was silenced by DNA methylation during differentiation…
- 11-10-2018Background: Bone is a preferential site for cancer metastases, especially from prostate and breast cancer. Here, metastasized cells are resistant…
- 10-10-2018Background: Periodontitis, a chronic inflammatory disease of the periodontium, is characterized by osteoclast-mediated alveolar bone destruction. Gingival fibroblasts (GFs) present…
- 11-09-2018BackgroundGlucocorticoids exert a myriad of metabolic effects mediated predominantly via binding to the glucocorticoid receptor (GR). The GR is known…
- 07-09-2018Aim: The endocannabinoid system (ECS) is involved in various metabolic functions, such as nutrient transport and energy storage. The cannabinoid…
- 07-09-2018BackgroungAfter stress exposure, prolonged or excessive exposure to glucocorticoids has been consistently related to increased vulnerability to psychopathologic disorders (Zalachoras,…
- 06-09-2018Background Glucocorticoids regulate pivotal processes such as metabolism and inflammation via the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR).…
- 05-09-2018Glucocorticoids potently enhance memory consolidation after emotional events, in a strictly noradrenaline-dependent way. This suggests an interaction of two transcription…