- 15-08-2019Metastatic castration-resistant prostate cancer (CRPC) remains a clinical challenge despite antitumoral therapies such as taxane chemotherapeutics, enzalutamide, and abiraterone acetate.…
- 23-11-201825-hydroxyvitamin D is mainly susceptible to hydroxylation on two positions. Hydroxylation on the 1-position by CYP27B1 yields the hormonally active…
- 14-11-2018Background: Type 2 Diabetes Mellitus (T2DM) is associated with an increased risk for cardiovascular disease. Postprandial hyperlipemia as characteristic for…
- 13-11-2018A.M.A. Berends, E. Buitenwerf, E.G. Gruppen, W. J. Sluiter, S.J.L. Bakker, M.A. Connelly, M.N. Kerstens, R.P.F. Dullaart. Department of Endocrinology,…
- 08-11-2018Short-term high-dose, but not low-dose, corticosteroid treatment reduces serum sclerostin levels. Renate T de Jongh1, Daniel van Raalte1, Martin den…
- 07-11-2018Background Hypothalamic-pituitary (HP) dysfunction after craniospinal irradiation (CSI) is frequently observed in childhood brain tumor survivors (CBTS). The risk increases…
- 07-11-2018Objective: Preterm birth is the most important risk factor for child morbidity and mortality worldwide. We aimed to study if…
- 07-11-2018Introduction Biallelic loss of function (LoF) mutations in the leptin receptor gene (LEPR) cause a striking phenotype of extreme early-onset…
- 07-11-2018Introduction Pediatric obesity is a major health problem. It is generally thought that it is rarely caused by an underlying…
- 07-11-2018RATIONALEA history of optic chiasm compression in patients with sellar tumors is associated with an altered sleep-wake rhythm. The optic…
