- 27-10-2023Background Optimal cortisol replacement therapy for patients with adrenal insufficiency (adr-ins) should mimic the cortisol diurnal rhythm. The standard of…
- 26-10-2023Objectives: Non-medullary thyroid cancer (NMTC) is the most common endocrine malignancy. Patients with advanced radioiodine refractory disease have poor prognosis…
- 18-08-2023Melanocortin 2 receptor accessory protein 2 (MRAP2) is a membrane-bound protein expressed in the hypothalamus, modulating the function of appetite-regulating…
- 01-12-2022PurposeWe recently have shown that a flattened glucocorticoid (GC) circadian rhythm in itself induces an osteoporotic phenotype in mice. Here,…
- 01-12-2022In the EU, 15 million people annually take systemic glucocorticoids (GCs) such as dexamethasone. GCs bind to the glucocorticoid receptor…
- 30-11-2022The circadian timing system coordinates daily cycles in physiological functions, including glucose metabolism and insulin sensitivity. However, how continuous enteral…
- 30-11-2022New treatment options are needed to prolong the life of patients with end-stage prostate cancer (PCa) that is resistant to…
- 30-11-2022Huntington’s Disease (HD) is a genetic neurodegenerative disease caused by a mutation in the huntingtin gene. Mutant huntingtin (mHtt) leads…
- 30-11-2022Huntington’s Disease (HD) is a genetic neurodegenerative disease caused by a mutation in the huntingtin gene. Mutant huntingtin (mHtt) leads…
- 29-11-2022BackgroundMedullary thyroid carcinoma (MTC) is a neuroendocrine tumor derived from the parafollicular C-cells of the thyroid gland. In patients with…
